Phenobarbital FDA Link

A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.

Also Known As:

Luminal; Gardenal; Phenobarbital Sodium; Hysteps; Phenobarbital, Monosodium Salt; Phenylethylbarbituric Acid; Acid, Phenylethylbarbituric; Monosodium Salt Phenobarbital; Sodium, Phenobarbital; Phenemal; Phenobarbitone; Phenylbarbital; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-

Pharmalogical Action Categories:

Anticonvulsants
Cytochrome P-450 CYP2B6 Inducers
Cytochrome P-450 CYP3A Inducers
Excitatory Amino Acid Antagonists
GABA Modulators
Hypnotics and Sedatives

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Barbiturates: 1074
        Phenobarbital: 21141

L D Hillis Selected Research

L D Hillis Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure